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Registros recuperados: 11 | |
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Kritski,Afrânio; Fujiwara,Paula I.; Vieira,Maria Armanda; Netto,Antonio Ruffino; Oliveira,Martha Maria; Huf,Gisele; Squire,S. Bertel. |
In this manuscript, we report the current situation of tuberculosis globally and in Brazil, the need for new strategies toward tuberculosis control, focusing on new diagnostic technologies. Critical comments are given on the state of the art regarding the evaluation of new health technologies, degree of scientific evidence needed, evaluation of clinical impact, cost-effectiveness of incorporation into the health system and the social impact. |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Tuberculosis; Diagnostics; Impact; Evidence; Policy; Innovation; Regulatory agency. |
Ano: 2013 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702013000200015 |
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Burge, Colleen A.; Friedman, Carolyn S.; Getchell, Rodman; House, Marcia; Lafferty, Kevin D.; Mydlarz, Laura D.; Prager, Katherine C.; Sutherland, Kathryn P.; Renault, Tristan; Kiryu, Ikunari; Vega-thurber, Rebecca. |
Linking marine epizootics to a specific etiology is notoriously difficult. Recent diagnostic successes show that marine disease diagnosis requires both modern, cutting-edge technology (e.g. metagenomics, quantitative realtime PCR) and more classic methods (e.g. transect surveys, histopathology and cell culture). Here, we discuss how this combination of traditional and modern approaches is necessary for rapid and accurate identification of marine diseases, and emphasize how sole reliance on any one technology or technique may lead disease investigations astray. We present diagnostic approaches at different scales, from the macro (environment, community, population and organismal scales) to the micro (tissue, organ, cell and genomic scales). We use disease... |
Tipo: Text |
Palavras-chave: Marine disease; Aetiology; Diagnostics; Marine epizootics. |
Ano: 2016 |
URL: http://archimer.ifremer.fr/doc/00314/42536/41911.pdf |
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Cox, Michael; Dartmouth College; michael.e.cox@dartmouth.edu. |
I attempt to demonstrate that the concept of institutional fit and the closely related approach of institutional diagnosis can be improved with the process of formalization. In this context, the concept of fit is interpreted as a way of expressing certain theoretical propositions that relate a set of variables with each other and with an outcome. This perspective is demonstrated through the use of the Web Ontology Language to express several "theories of fit." Using a formal language to describe types of fit and their associated theories is argued to have much potential for advancing the scientific study of social-ecological systems. |
Tipo: Peer-Reviewed Reports |
Palavras-chave: Diagnostics; Formalization; Institutional fit; Social-ecological systems. |
Ano: 2012 |
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Soares,Killarney Ataide; Urdapilleta,Ada Amália Ayala; Santos,Gilcilene Maria dos; Carneiro,Andréa Lisboa; Gomes,Ciro Martins; Roselino,Ana Maria; Sampaio,Raimunda Nonata Ribeiro. |
Background: Several tests are performed to obtain better accuracy when diagnosing American tegumentary leishmaniasis (ATL). It is believed that antigens released via secretion, excretion and metabolism are more specific than are antigens released by the lysis of Leishmaniaparasites. Such antigens are known as exo-antigens (exo-Ag) and are formed from products released by cultured parasites in a way that is similar to that in which they cause infections in hosts.Objective: We attempted to validate a Leishmania mexicanaELISA exo-Ag for ATL diagnosis in Midwestern Brazil.Methods: A total of 281 patients were included in the study. We analysed pre-treatment blood from 98 ATL patients; out of those, 85.7% and 14.3% had cutaneous and mucosal forms,... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Diagnostics; Disease control; Infectious disease; Leishmaniasis. |
Ano: 2015 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702015000300302 |
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Registros recuperados: 11 | |
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